This page was reviewed under our medical and editorial policy by
Frederick L. Durden, Jr, MD, Plastic and Reconstructive Surgeon & Microsurgical Reconstructive Surgeon
This page was updated on February 24, 2023.
Although a biopsy may be used to diagnose and remove some of your melanoma, your doctor is likely to recommend a surgical procedure known as wide excision. Considered a fairly minor surgery, wide excision involves removing the entire area that’s suspected to be cancerous, along with some margins (normal, healthy tissue) to be sure all the cancer is removed.
Wide excision is also performed when your melanoma has:
During a biopsy, doctors typically make a narrow incision, about 1 to 2 mm in length. Wide excision requires a larger incision so that your surgeon is sure to remove the entire tumor and the healthy tissue surrounding it.
Your surgeon determines how much tissue needs to be removed based on the answer to these questions:
Wide excision is likely to be performed as an outpatient day procedure, under a local anesthetic. The area is numbed so you don’t feel anything, but you’re kept awake. The small area is closed with stitches or clips.
The procedure may be done under general anesthesia if your surgeon needs to see whether your lymph nodes are involved or if the area that needs to be removed is large.
If a large area of skin is removed, you may need a skin graft to cover what was taken. During a skin graft, surgeons take healthy skin from elsewhere on the body and use it to cover the skin that was lost.
After a wide excision procedure, you’re likely to feel some tightness while your skin heals. You also may feel tenderness in the area.
If you have stitches, they may need to be removed at your doctor’s office.
Your doctor may request a follow-up appointment within four to six weeks to see how the wound is healing.
Preparation depends on whether your wide excision will be performed under local or general anesthesia.
If you’re having general anesthesia:
With local anesthesia, there’s not much you need to change or do beforehand. Getting a good night’s sleep and eating a healthy diet are always a good idea. Ask with your care team about any special instructions.
After the procedure, drink clear liquids and eat light to prevent stomach upset.
Give the area time to heal. Ask your doctor when it’s safe to resume your normal activities, including exercise.
The area that was anesthetized may stay numb for several hours afterward.
After your surgery, you may need:
Even though it’s a minor procedure, wide excision is still surgery. Watch out for:
If you have any questions about how well you’re healing, you may not want to wait until your four- to six-week follow-up appointment with your doctor. Call your care team if you notice anything you’d like to discuss.
Wide excision is typically recommended as a treatment option for localized melanoma. Overall, the five-year survival rate for localized melanoma is 99 percent, according to the American Cancer Society.
Your surgeon doesn’t want to remove skin unnecessarily. However, the smaller the margins, the greater the risk of melanoma recurring. Talk to your doctor about how much area may be surgically removed and why.
After your doctors have removed all the melanoma that they see while operating and they receive the report from the pathology lab, they may recommend chemotherapy to lower any chances of melanoma returning.