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Leo David Wang,

Pediatric Hematologist-Oncologist

Biography photo
Location
City of Hope Duarte
1500 East Duarte Road
Duarte, CA 91010
Specialties
Hematologic Oncology
Pediatric Hematology Oncology
Education
Medical school:
Degrees
  • B.S., Molecular Biophysics and Biochemistry, Yale University, New Haven, CT

  • Ph.D., University of Chicago Committee on Immunology (Marcus Clark, advisor), University of Chicago, Chicago, IL

  • M.D., University of Chicago Pritzker School of Medicine, University of Chicago, Chicago, IL

Fellowship
  • Pediatric Hematology/ Oncology/Stem Cell Transplant, Dana Farber/Children’s Hospital Cancer Center, Boston, MA

  • Postdoctoral Fellow, Amy Wagers, PI, Joslin Diabetes Center and Harvard Stem Cell Institute

Residency
  • Pediatrics, Children’s Hospital of Philadelphia

Internship
  • Pediatrics, Children’s Hospital of Philadelphia, PA

Professional Experience
  • 2023-Present, Program Director, City of Hope Alpha Stem Cell Clinic, City of Hope, Duarte, CA

  • 2023-present, Associate Professor, Pediatrics and Immuno-Oncology, City of Hope, Duarte, CA

  • 2016-2023, Assistant Clinical Professor, Department of Immuno-Oncology and Department of Pediatrics, City of Hope, Duarte, CA

  • 2011-2016, Instructor in Pediatrics, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, Boston, MA

Academic Appointments
  • Associate Professor, Department of Immuno-Oncology
  • Associate Professor, Department of Pediatrics
  • Director, City of Hope Alpha Clinic
  • Director, Clinical Gene Therapy Program
About Me

Dr. Wang leads a research laboratory focused on harnessing the immune system to fight cancer in children. Work there uses cellular engineering to reprogram the body’s own immune cells to kill tumor cells, and to teach reengineered cells to adapt to tumors as they change and evolve to try to escape from therapy. Dr. Wang also leads clinical trials using these living medicines to treat children with brain tumors and other forms of deadly cancer, and uses the information learned from these trials to improve the design and implementation of next-generation therapies. The lab’s research has won multiple honors and awards, and Dr. Wang is always available to talk to families who have questions. For more information, please email pediatrictrials@coh.org

Dr. Wang is also the Director of City of Hope’s Alpha Clinic, one of nine sites throughout California forming a CIRM-funded network to make it easier for patients to access and enroll in stem cell and regenerative medicine clinical trials. In this capacity, he works with colleagues at City of Hope and throughout California to build robust and sustainable clinical trial infrastructure capable of providing cutting-edge care to all Californians.

Dr. Wang earned his undergraduate degree in molecular biophysics and biochemistry from Yale University, followed by his Ph.D. and medical doctorate at University of Chicago. He completed internship and residency at Children’s Hospital of Philadelphia, and fellowship in pediatric hematology/oncology/stem cell transplantation fellowship at the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, where he pursued postdoctoral research in the laboratory of Amy Wagers at the Harvard Stem Cell Institute.

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