This page was reviewed under our medical and editorial policy by
Maurie Markman, MD, President, Medicine & Science
This page was updated on June 3, 2022.
Finding gallbladder cancer while it is still at an early stage increases the chance for better outcomes. While symptoms usually do not develop until a tumor has grown or the cancer is at an advanced stage, being aware of the possible symptoms and discussing them with a doctor right away may improve chances of catching it and treating it at an earlier stage.
Possible gallbladder cancer symptoms include:
Most people with gallbladder cancer experience pain, which is usually located in the upper or upper-right abdomen. Some patients describe it as a sharp pain, while others describe it as a “dragging feeling.”
Because the gallbladder is located under the liver, a gallbladder tumor may block the liver’s bile duct and prevent bile from draining into the intestines. As a result, bilirubin, a yellow-orange pigment in the bile, may accumulate in the blood and body tissues, potentially in causing the skin and whites of the eyes to take on a yellowish tint, a condition known as jaundice.
The gallbladder is surrounded by other organs, so it may be hard to notice an increase in its size. Sometimes a doctor may feel it during a physical examination. Doctors may also detect an increase in gallbladder size through imaging tests, such as an ultrasound.
Gallbladder tumors may be associated with other symptoms, such as:
Gallbladder cancer is rare. Many other conditions may cause the symptoms described above. People with gallstones may experience some of the same challenges, including severe abdominal pain. Conditions such as hepatitis and certain medications, including oral contraceptives, anabolic steroids and penicillin, may cause jaundice. Abdominal swelling may occur for a variety of reasons.
Next topic: What are the types of gallbladder cancer?